ACTIVE TRANSPORT:
- Active transport uses ATP to pump molecules against the concentration gradient. Transport occurs from a low conc. of solutes to high conc. of solute.
- Requires cellular energy.
- Types of transport include endocytosis, cell membrane/ sodium potassium pump and exocytosis.
- Function : Transport molecules against the conc. gradient so more of the substance is inside the cell (i.e., a nutrient) or outside the cell (i.e., waste) than normal. Disrupts equilibrium established by diffusion.
- Types of particles transported : Proteins, ions, large cells, complex sugars
- Requires carrier proteins. Matrix or permeases of the membrane are not involved.
- It is highly selective.
- It is rapid process.
- It is unidirectional.
- It is reduced or stopped by O2 deficiency.
- Metabolic inhibitors stop active transport.
- Decrease in temp. decreases it.
- E.g., Phagocytosis, pinocytosis, Na+/K+ pump, secretion of a substance into the bloodstream
PASSIVE TRANSPORT:
- Movement of molecules occurs down the conc. gradient. It goes from high to low conc. in order to maintain equilibrium in the cells.
- Does not require cellular energy.
- Types of transport includes diffusion, facilitated diffusion and osmosis.
- Function : Maintains dynamic equilibrium of water, gases, nutrients, wastes etc. between cells and extracellular fluid; allows for small nutrients and gases to enter/exit. No net diffusion/osmosis after equilibrium is established.
- Types of particles transported: Anything soluble in lipids, small monosaccharides, water, O2, CO2, hormones etc.
- Carrier proteins are not involved. It takes place through matrix/channels/permeases.
- It is partly non-selective. All diffusible substances can be transported according to their conc. gradient.
- It is comparatively slower process.
- It is bidirectional
- Unaffected by O2 content.
- Metabolic inhibitors do not influence passive transport.
- Not affected by temp.
- E.g., Diffusion, facilitated diffusion, osmosis
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