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HYPERTROPHIC
OBESITY
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HYPERPLASTIC
OBESITY
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1. Cell size increases.
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1. Cell number increases.
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2. Adipose tissue are larger than normal.
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2. More of the adipose cells are present.
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3. It is strongly correlated with diet.
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3. It depends on genetics more.
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4. It occurs early in the obesity progression to meet the need for
additional fat storage capacity.
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4. It is triggered by hypertrophy.
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5. Main contributor to fat as mass increases.
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5. Does not contribute much to obesity because it occurs in small
cells that have smaller volume of fat stored.
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6. Some specific metabolic properties e.g., insulin resistance, and
adipokine secretion depend on the precise cell-size distribution rather than
the mean cell size.
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6. Such metabolic properties does not depend on cell number.
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Thursday, December 20, 2018
differences between hypertrophic and hyperplastic obesity.
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PHASE CONTRAST MICROSCOPY
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