Saturday, September 29, 2018

Differentiate between COP I TRANSPORT and COP II TRANSPORT

COP I TRANSPORT :

1. COP I is a protein complex that coats vesicles transporting protein from the cis end of the Golgi complex back to Rough Endoplasmic Reticulum (RER).
2. This type of transport is retrograde.
3. Initiates budding process on cis - end of Golgi complex.
4. Consists of large protein subcomplexes that are made of 7 different protein sub units : Alpha, Beta, Beta', Gamma, Delta, Epsilon and Tau
5. GTPase activity is carried out by ADP Ribosylation Factor (ARF) during the budding process.

COP II TRANSPORT

1. COP II is a protein complex that coats vesicles transporting proteins from the RER to Golgi apparatus.
2. This type of transport is anterograde.
3. Initiates budding process on Rough Endoplasmic Reticulum.
4. Made of 4 different protein subunits. 2 proteins Heterodimers from the coal complex  are -
Sec 23p/ Sec 24p and Sec 13p/ Sec 31p
5. GTPase activity is carried out by GTPase Sar Ip during the budding process.   

No comments:

Post a Comment

PHASE CONTRAST MICROSCOPY

Introduction: Most cells are too small to be seen by the naked eyes, the study of cells has depended heavily on the use of microscopes. Mi...