Saturday, August 25, 2018

Differences between replication and transcription.

REPLICATION:

  • The process of making two daughter strands where each daughter strand contains half of the original DNA double helix.
  • The purpose of replication is to conserve the entire genome for next generation.
  • Enzyme required- DNA Polymerase.
  • It occurs- in the S phase of cell cycle. , Along the both strands of DNA.
  • It is the preparation for cell division.
  • Replicated DNA strand remains hydrogen bonded to its template DNA strand.
  • This process requires RNA primer to start the process.
  • Product remains within the nucleus.
  • It involves unwinding and splitting of entire genome.
  • More accurate than transcription.
  • Speed is generally more as compared to transcription. 

TRANSCRIPTION:

  • The process of synthesis of RNA using DNA as a template is called transcription.
  • Purpose- To make RNA copies of individual genes.
  • Enzyme required- RNA Polymerase.
  • Occurrence- in G1 and G2 phases of cell cycle, Along one strand of DNA. 
  • It is the preparation for protein translation.
  • Transcribed RNA strand separates from its DNA template strand.
  • No primer is required.
  • Most part of product i.e., mRNA passes from nucleus to cytoplasm.
  • It involves unwinding of only those genes which are to be transcribed.
  • Comparatively less accurate than replication.
  • Speed is less as compared to replication.

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