Thursday, August 2, 2018

LIVER CIRRHOSIS

Cirrhosis is a condition in which the liver does not function properly due to long term damage. This damage is characterized by the replacement of normal tissues by scar tissue. Typically, the disease develops slowly over months or years. As the disease woruns, a person may become tired, weak, itchy, have swelling in lower legs and have fluid build-up in the abdomen.
Cirrhosis is most commonly caused by alcohol, hepatitis B, hepatitis C and non-alcoholic fatty liver diseases.
The pathological hallmark of cirrhosis is the development of scar tissue that replaces normal parenchyma. This scar tissue blocks the portal flow of blood through the organ, raising blood pressure and distributing normal function. As this cascade of processes continues, fibrous tissue bands separate hepatocyte nodules, which eventually replace the entire liver architecture leading to decreased blood flow throughout. The spleen becomes congested and portal hypertension is responsible for the most severe complications. A healthy diet is encouraged and alcohol consumption is strictly prohibited as a part of treatment.

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